Date of establishment

Drug analysis and development center has been established since June 2014.

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Location

沙巴体育 College of Pharmaceutical sciences, 沙巴体育

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Objective

To share the research infrastructure to others who could not establish the sophisticated infrastructure at their level for their research needs

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Conduct

1. The Requester shall submit the request in the prescribed format to ‘The Principal MCOPS’ for sample analysis either for drug estimations, characterizations or drug evaluation.?
2. Depending upon the type of analysis, the request will be referred to the appropriate location for the further processing.
3. The HOD of the location concerned will analyse the request and puts a note for the appropriate charges to be levied for the analysis.
4. The requester shall pay the charges in 沙巴体育 University finance and submit the request form to the location concerned along with the sample and payment receipt.
5. The location concerned will conduct the test/s in reasonable time limit and submits the report to the requester concerned.

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Contact details

MCOPS office: Phone:+91-820-2922482, E-mail: info.mcops@manipal.edu

1. Department of Pharmaceutical Chemistry: Dr Suvarna G Kini,?suvarna.gk@manipal.edu
2. Department of Pharmacology: Dr Nandakumar K,?nandakumar.k@manipal.edu
3. Department of Pharmaceutics:? Dr Srinivas Mutalik, ss.mutalik@manipal.edu
4. Department of Pharmacognosy: Dr Richard Lobo,?richard.lobo@manipal.edu
5. Department of Pharmaceutical Quality Assurance: Dr Sudheer Moorkoth,?moorkoth.s@manipal.edu
6. Department of Pharmaceutical Biotechnology: Dr Raghu Chandrashekar H,?raghu.c@manipal.edu

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For Services and Charges Click here

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Test Details

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Department of Pharmaceutical Chemistry (PCH)

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Test Code ? ? ? ? ? ? ? ? ?Test Details

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PCH1 ? ? ? ? ? ? ? ? ? ? ? ? ?GC-Qualitative

PCH2 ? ? ? ? ? ? ? ? ? ? ? ? ?HPLC-Qualitative

PCH3 ? ? ? ? ? ? ? ? ? ? ? ? ?HPLC-Method Development

PCH4 ? ? ? ? ? ? ? ? ? ? ? ? ?UV Spectroscopy-Qualitative

PCH5 ? ? ? ? ? ? ? ? ? ? ? ? ?UV Spectroscopy-Method Development

PCH6 ? ? ? ? ? ? ? ? ? ? ? ? ?FTIR Spectroscopy

PCH7 ? ? ? ? ? ? ? ? ? ? ? ? ?TLC

PCH8 ? ? ? ? ? ? ? ? ? ? ? ? ?Ash Value

PCH9 ? ? ? ? ? ? ? ? ? ? ? ? ?Sugars per test per sample

PCH10 ? ? ? ? ? ? ? ? ? ? ? ?Saponification Value

PCH11 ? ? ? ? ? ? ? ? ? ? ? ?Iodine Value

PCH12 ? ? ? ? ? ? ? ? ? ? ? ?Acid Value

PCH13 ? ? ? ? ? ? ? ? ? ? ? ?Total Solids

PCH14 ? ? ? ? ? ? ? ? ? ? ? ?Extractive Values

PCH15 ? ? ? ? ? ? ? ? ? ? ? ?Water Testing

PCH16 ? ? ? ? ? ? ? ? ? ? ? ?Formulation analysis by Titrimetry

PCH17 ? ? ? ? ? ? ? ? ? ? ? ?Alcohol Content

PCH18 ? ? ? ? ? ? ? ? ? ? ? ?Refractive Index

PCH19 ? ? ? ? ? ? ? ? ? ? ? ?Specific Gravity/Density

PCH20 ? ? ? ? ? ? ? ? ? ? ? ?pH testing

PCH21 ? ? ? ? ? ? ? ? ? ? ? ?Chemical Identification Test – per class

PCH22 ? ? ? ? ? ? ? ? ? ? ? ?Boiling Point

PCH23 ? ? ? ? ? ? ? ? ? ? ? ?Metal ion – qualitative

PCH24 ? ? ? ? ? ? ? ? ? ? ? ?Loss on Drying

PCH25 ? ? ? ? ? ? ? ? ? ? ? ?Poison Testing

PCH26 ? ? ? ? ? ? ? ? ? ? ? ?Monograph Analysis

PCH27 ? ? ? ? ? ? ? ? ? ? ? ?Glass Apparatus Fabrication/Repair

PCH28 ? ? ? ? ? ? ? ? ? ? ? ?Computational Services for Drug Design

PCH29? ? ? ? ? ? ? ? ? ? ? ??Cyclic Volta meter Measurement

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Department of Pharmacology (PHA)

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Test Code?????? ??????????? Test Details

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PHA1? ??????????? ??????????? Flow Cytometry-for processed sample

PHA2? ??????????? ??????????? MTT-Cell Viability Assay (for the available Cell line with MCOPS)

PHA3? ??????????? ??????????? Flow Cytometry-Cell Cycle Analysis (only for MCF-7 and HCT-116)

PHA4? ??????????? ??????????? Western Blotting running charges per plot

PHA5? ??????????? ??????????? Acute Toxicity as per OECD guidelines (not as per GLP standards)

PHA6? ??????????? ??????????? Anti-inflammatory Acute Study with 3 dose

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Department of Pharmaceutics (PCE)

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Test Code?????? ??????????? Test Details

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PCE1?? ??????????? ??????????? Particle size-nanometer scale by Malvern Zetasizer (includes zeta potential)

PCE2?? ??????????? ??????????? Particle size-micrometer scale by QBIDEX-Scatteroscope I

PCE3?? ??????????? ??????????? Viscosity measurement by Brookfield? Viscometer (up to 30 thousand CPS only)

PCE4?? ??????????? ??????????? DSC Analysis

PCE5? ? ? ? ? ? ? ? ? ? ? ? ? ?FTIR Analysis

PCE6? ? ? ? ? ? ? ? ? ? ? ? ? ?Hot Melt Extrusion sytem

PCE7? ? ? ? ? ? ? ? ? ? ? ? ? ?Analysis of biological samples

PCE8? ? ? ? ? ? ? ? ? ? ? ? ? ?HPLC analysis

PCE9? ? ? ? ? ? ? ? ? ? ? ? ? ?HPLC analytical method development/ validation

PCE10? ? ? ? ? ? ? ? ? ? ? ? ??HPLC analytical method development & validation

PCE11? ? ? ? ? ? ? ? ? ? ? ? ? ?Preclinical Pharmacokinetics Studies

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(Quantitative)(Qualitative)Department of Pharmacognosy (PCO)

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Test Code?????? ??????????? Test Details

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PCO1? ??????????? ??????????? Phytochemical Evaluation-Moisture content

PCO2? ??????????? ??????????? Phytochemical Evaluation-Ash value /method/sample

PCO3? ??????????? ??????????? Phytochemical Evaluation Ext. value/ method/sample

PCO4? ??????????? ??????????? In vitro Antioxidant Studies-DPPH

PCO5? ??????????? ??????????? In vitro Antioxidant Studies-ABTS

PCO6? ??????????? ??????????? In vitro Antioxidant Studies-Orthophenol

PCO7? ??????????? ??????????? In vitro Antioxidant Studies-Total antioxidant

PCO8? ??????????? ??????????? In vitro Antioxidant Studies- H₂O₂

PCO9? ??????????? ??????????? Anatomical Studies and Photo documentation per sample

PCO10 ? ? ? ? ? ? ? ? ? ? ? ?Phytochemical Screening

PCO11 ? ? ? ? ? ? ? ? ? ? ? ?Lyophyllization of Herbal Ext.

PCO12 ? ? ? ? ? ? ? ? ? ? ? ?HPTLC Analysis-Finger print

PCO13 ? ? ? ? ? ? ? ? ? ? ? ?HPTLC Analysis-Finger print with Marker

PCO14 ? ? ? ? ? ? ? ? ? ? ? ?HPTLC Analysis-Method Development and Validation

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Department of Pharmaceutical Quality Assurance (PQA)

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Test Code?????? ??????????? Test Details

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PQA1? ??????????? ??????????? GC-Qualitative

PQA2? ??????????? ??????????? GC-Method Development

PQA3? ??????????? ??????????? GC-Validation of Method

PQA4? ??????????? ??????????? HPLC-Qualitative

PQA5? ??????????? ??????????? HPLC-Method Development

PQA6? ??????????? ??????????? HPLC-Validation of Method per sample

PQA7? ??????????? ??????????? HPLC-Qualitative

PQA8? ??????????? ??????????? HPTLC-Method Development

PQA9? ??????????? ??????????? HPTLC-Validation of Method per sample

PQA10??????????? ??????????? UV Spectroscopy-Qualitative

PQA11??????????? ??????????? UV Spectroscopy-Method Development

PQA12??????????? ??????????? UV Spectroscopy- Validation of Method per sample

PQA13??????????? ??????????? Florescence Spectroscopy-Qualitative

PQA14? ? ? ? ? ? ? ? ? ? ? ??Florescence Spectroscopy-Method Development and validation

PQA15? ? ? ? ? ? ? ? ? ? ? ??Florescence Spectroscopy- Quantitative analysis (per sample)

PQA16??????????? ??????????? DSC

PQA17??????????? ??????????? FTIR Spectroscopy

PQA18??????????? ??????????? TLC

PQA19??????????? ??????????? Ash Value

PQA20??????????? ??????????? Sugars per test per sample

PQA21??????????? ??????????? Saponification Value

PQA22??????????? ??????????? Iodine Value

PQA23??????????? ??????????? Acid Value

PQA24??????????? ??????????? Total Solids

PQA25??????????? ??????????? Extractive Values

PQA26??????????? ??????????? Moisture Content by Karl Fischer method

PQA27??????????? ??????????? Water Testing

PQA28??????????? ??????????? Formulation analysis by Titrimetry

PQA29??????????? ??????????? Alcohol Content

PQA30??????????? ??????????? Refractive Index

PQA31??????????? ??????????? Specific Gravity/Density

PQA32??????????? ??????????? pH testing

PQA33??????????? ??????????? Chemical Identification Test – per class

PQA34??????????? ??????????? Weight Variation Test

PQA35??????????? ??????????? Tablet Hardness

PQA36??????????? ??????????? Disintegration Test

PQA37??????????? ??????????? Viscosity

PQA38??????????? ??????????? Boiling Point

PQA39??????????? ??????????? Metal ion – qualitative

PQA40??????????? ??????????? Loss on Drying

PQA41??????????? ??????????? Dissolution Testing-Official method

PQA42??????????? ??????????? Dissolution Testing-Official method is not available

PQA43? ? ? ? ? ? ? ? ? ? ? ??MS – Spectra Simple Matrix

PQA44? ? ? ? ? ? ? ? ? ? ? ??MS – Spectra Complex Matrix

PQA45? ? ? ? ? ? ? ? ? ? ? ? LCMS – MS method development and Validation

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Department of Pharmaceutical Biotechnology (PBT)

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Test Code ? ? ? ? ? ? ? ? ? Test Details

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PBT1?? ??????????? ??????????? Antioxidant? Assays (DPPH/ABTS/Nitric Oxide/Alkaline DMSO)-One method

PBT2?? ??????????? ??????????? Antioxidant? Assays (DPPH, ABTS, Nitric Oxide, Alkaline DMSO)-Four methods

PBT3? ? ? ? ? ? ? ? ? ? ? ? ? ?Antioxidant assay using cell lines (DCFH-DA) per compound per cell line (at least two samples)? ? ?

PBT4? ? ? ? ? ? ? ? ? ? ? ? ? ?Determination of Minimum Inhibitory Concentration (MIC as per CLSI guidelines) Per compound/ organism (against one organism available in the department)?

PBT5? ? ? ? ? ? ? ? ? ? ? ? ? ?Antibacterial and Antifungal studies (against two Gram +ve and two Gram -ve bacteria, two fungi and one yeast, available in the department) by Agar diffusion method (sensitivity) (Rs 250/- sample/ organism)??

PBT6? ? ? ? ? ? ? ? ? ? ? ? ? Cytotoxicity Studies (MTT, SRB Assays) one Assay, one available cell line, one compound

PBT7? ? ? ? ? ? ? ? ? ? ? ? ? Nuclear staining studies for one compound, one available cell line and one dye (Per sample two images)

PBT8? ? ? ? ? ? ? ? ? ? ? ? ??DNA Fragmentation Assay (One compound, one available cell line)

PBT9? ? ? ? ? ? ? ? ? ? ? ? ??PCR (with DNA sample and primer sequence is to be provided by the customer)

PBT10? ? ? ? ? ? ? ? ? ? ? ? ?Determination of microbial limit (As per IP) per sample. (If any inhibitory medicament is present, the charges will be decided upon discussion)

PBT11? ? ? ? ? ? ? ? ? ? ? ? ? Sterility test (direct inoculation method) (As per IP) per sample. (If any inhibitory medicament is present, the charges will be decided upon discussion)

PBT12? ? ? ? ? ? ? ? ? ? ? ? ?Microbial assay of antibiotics by tube dilution/ Agar diffusion assay

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