Reproductive Medicine

Department of Reproductive Medicine & Surgery, KMC, 沙巴体育

About the Department

The Department of Reproductive Medicine & Surgery (RMS), previously known as 沙巴体育 Assisted Reproduction Center (MARC) has been offering a wide range of treatment programs for subfertile couples seeking assisted conception. It is backed by the experience of expert doctors and scientists who have taken specialized training abroad and have been working with subfertility problems since 1990. The pioneering technological improvements make the department one of the most advanced centers for the treatment of infertility in India.

The centre has a fully equipped andrology laboratory for male subfertility evaluation and semen banking for short-term and long-term storage. Embryology laboratory with all modern facilities including micromanipulation and laser hatching is another highlight of the center. Advanced techniques like oocyte pickup, ovarian cryopreservation, laparoscopic and hysteroscopic surgeries is done.?

Adjunct Faculty

SN	Name	Designation
1.	Dr Siya Sharan Sharma	Consultant in Gynaecology & Obstetrics Department of Obstetrics & Gynaecology The Queen Elizabeth Hospital Gayton Road, Kings Lynn, PE30 4ET, UK
2.	Dr Howard Carp ?	Senior Physician Obstetrics & Gynaecology Sheba Medical Center Tel Hashomer, Israel
3.	Prof. Juan Antonio García Velasco	Full Professor of Obstetrics & Gynaecology Director IVI Madrid Av. Del Talgo, 68, 28023 Madrid, Spain

PhD Awarded/Ongoing

Phd Guide/Co-Guide:? , Professor & Head

Sl.No.	Guide / Co-Guide	Candidate Name	Year
1	Dr Pratap Kumar	Ms Ansha Patel ?	2019
2	Dr Pratap Kumar	Ms Azadeh Bagheri ?	2018
3 ?	Dr Pratap Kumar	Mr Krishnananda Nayak ?	2018
4	Dr Pratap Kumar	Ms Preetha R ?	2016 ?
5	Dr Pratap Kumar	Mr Dayanidhi Kumar ?	2015 ?
6 ?	Dr Pratap Kumar	Mrs Gayathri Nayak ?	2013 ?
7	Dr Pratap Kumar	Ms Varshini J	2011 ?
8	Dr Pratap Kumar	Mr Dinesh Upadhya ?	2010 ?
9	Guide	Prof (Mrs) Bharati V Bellare ?	2003 ?

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Services Offred

·??????? Induction of Ovulation

·??????? Ultrasound & Doppler

·??????? Transvaginal Sonographic Procedures

·??????? Intra Uterine Insemination

·??????? In Vitro Fertilization with Embryo Transfer (IVF-ET)

·??????? Intra Cytoplasmic Sperm Injection (ICSI)

·??????? Laser assisted hatching

·??????? Vasal, Epididymal & Testicular Sperm Extraction (MESA/TESA)

·??????? Embryo and Semen Banking

·??????? Computer Aided Sperm Analysis (CASA)

·??????? Sperm DNA damage evaluation

·??????? Oncofertility

·??????? Laparoscopic & Hysteroscopic procedures

·??????? Comprehensive Male Infertility Evaluation and Treatment

·??????? Male Reproductive Laboratory

·??????? Donor Egg, Donor Sperm & Surrogacy

·??????? Blastocyst culture

·??????? Intracytoplasmic Morphologically Selected Sperm Injection (IMSI)

·??????? Time lapse imaging of embryos

·??????? Fertility preservation (ovarian & testicular tissue cryopreservation)

Assisted Reproductive Techniques

Intrauterine insemination

Intrauterine insemination (IUI) is a simple, less invasive technique in which the husband or donor sperm is placed in the womb using a catheter. IUI is indicated for the treatment of low sperm count or unexplained infertility.

In vitro fertilization with Embryo Transfer

In Vitro Fertilisation with Embryo Transfer (IVF) is a procedure that involves retrieving the eggs from the wife after sufficient medication to stimulate the ovaries to develop many follicles. The eggs are fertilized in the dish using husband’s sperm.

Intracytoplasmic sperm injection (ICSI)

Intracytoplasmic Sperm Injection (ICSI) is used to treat couples who previously had failure in achieving conception due to the male partner’s extremely low number of normal sperm or with unexplained infertility.

Third party reproduction - Donor Eggs, Donor Sperm and Surrogacy

For women experiencing failure of their ovarian function and women over age of 40 with poor quality eggs, the use of donated eggs from another woman may be the best option to achieve conception. Our semen bank provides donor sperm for use in IUI and IVF when the husband has no sperm or if he has any genetic disorders.

Laser Assisted Hatching

It is a process to assist the embryos to break the zona pellucida (ZP) using laser in order to attach to the womb to increase the chance of pregnancy.?

沙巴体育

The department focusses on research programmes for improving the quality of management of sub-fertile couples. 沙巴体育 works on animal models are being carried out and this is one of the IVF centers in the country associated with a university medical college.

List of ongoing projects:

S.No.

Title of the grant

Granting agency

Co-Investigator

Duration of the project

Targetted and Non-Targetted Approaches to Investigate Uterine Microenvironment in Women with Recurrent Implantation Failure

Indian Council of Medical 沙巴体育, New Delhi, India & National Institute for 沙巴体育 in Reproductive Health?(NIRRH),

Dr Pratap Kumar

Dr Anjali Suneel Mundkur

2021 -

Role of Placental Monocarboxylate Transporter 8 (MCT8) expression on adverse pregnancy outcomes in Indian population

Indian Council of Medical 沙巴体育, New Delhi, India

Dr Vidyashree G. Poojari

2021-2023

List of completed projects:

S.No.	Title of the grant	Granting agency	Principal Investigator / Co-Investigator	Duration of the project
1	An observational study to evaluate the follicular and endometrial response in couples with unexplained infertility undergoing micronized clomifene citrate stimulated intrauterine insemination	Walter Bushnell Laboratories Pvt Ltd., Uttarakhand, India ?	? Dr Pratap Kumar Principal Investigator ?	2017-2019
2	Clinical experience with micronized estradiol valetate tablets in endometrial preparation ?	Martin & Harries Pvt. Ltd., Haridwar	Dr Pratap Kumar Principal Investigator	2015-2016
3	Fertility preservation using Moringa oleifera leaf extract in mice treated with Chemotherapeutic agents and its mechanism	Indian Council of Medical 沙巴体育 (ICMR), New Delhi ?	? Dr Pratap Kumar Co-investigator	2012-2014
4	A study to evaluate the impact of different controlled ovarian stimulation protocols on physical and psychological burden in patients undergoing In-Vitro Fertilization/In-Vitro Cytoplasmic Sperm Injection	GVK Bioscience Pvt. Ltd., Gurgaon, India ?	Dr Pratap Kumar Principal Investigator	2012-13
5	Evaluation of laser manipulated embryos for their hatching potential, metabolic changes and laser induced effects	Indian Council of Medical 沙巴体育 (ICMR), Govt. of India	Dr Pratap Kumar Co-investigator	2011-2014
6	Intermediates of calcium signal process as oocytes activating agents and development of an optimum culture medium for mouse parthenotes	Department of Biotechnology (DBT), Govt. of India	Dr Pratap Kumar Co-investigator	2011-2013
7	The impact of chromosomal and sub-chromosomal sperm abnormalities on the embryonic development and Assisted Reproductive Technology (ART) outcome	Department of Science and Technology (DST), Govt. of India	Dr Pratap Kumar Co-investigator	2010-2013
8	Evaluation of sperm chromatin modification, sperm methylation errors and reproductive toxicity in radiation health workers	Indian Council of Medical 沙巴体育 (ICMR), New Delhi	Dr Pratap Kumar Principal Investigator	2009-2012

Publications

1. Shaiesta Amreen, Pratap Kumar, Priyanka Gupta, Pragna Rao. Evaluation of oxidative stress and severity of endometriosis. Journal of Human Reproductive Sciences. January – March 2019 ;12(1);40-46.

2. Shubhashree Uppangala, Gail Fernandes, Sujith Raj Salian, Pratap Kumar, Riccardo Talevi, Guruprasad Kalthur, Satish Kumar Adiga. Reduced ovarian response to controlled ovarian stimulation is associated with increased oxidative stress in the follicular environment. Reproductive Biology; 20(3);September 2020:402-407.

3. Ansha Patel, PSVN Sharma, Pratap Kumar. “Application of Mindfulness-Based Psychological interventions in Infertility”. Journal of Human Reproductive Sciences. January-March 2020;13(1);1-21.

4. Spoorthy Venkatesh, Anjali M, Akhila Vasudeva, Pratap Kumar. “Sliding sign and gel sonovaginography: A sneak peek prior to laparoscopy in patients with endometriosis”.? Journal of Human Reproductive Sciences. May 2020;13(1);26-30.

5. Ansha Patel, PSVN Sharma, Pratap Kumar. Psychiatric disorders in Women seeking fertility treatments: A clinical investigation in India. 沙巴体育 Journal of Fertility and Sterility. April - June 2020;14(1);68-71.